Variation in TMEM106B in chronic traumatic encephalopathy
Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood.Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced Vacuum Motor Filter neuroinflammation during aging and with TDP-43-related neurodegenerative disease, and rs3173615, a missense coding SNP in TMEM106B, has been implicated as